ea0035p512 | Endocrine disruptors | ECE2014
Chevalier Nicolas
, Paul-Bellon Rachel
, Bouskine Adil
, Fenichel Patrick
Introduction: Testicular germ cell tumours are the most frequent cancer of young men. Epidemiological and clinical data have suggested that fetal or perinatal exposure to environmental endocrine disruptors (EEDs) with estrogenic effects, could participate to testicular germ cell carcinogenesis. However, EEDs (like bisphenol A (BPA) are often weak ligands for classical nuclear estrogen receptors.Using a human seminoma cell line (JKT-1), devoid of ERĪ±...